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Oxygen delivery equation.

Hi guys, ECC question here. I’m doing a bit of reading about critical cases and specifically shock, but I’ve never been able to quite get my head around the equation that explains oxygen delivery - that’s the DO2 = CaO2 x CO one. Can someone please explain it to me in plain English!

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Is the Coombs test actually useful?

At university we learnt about the Coombs test for IMHA, but I’ve heard many vets say that it’s not really worth doing. Is it still worth sending away for it in those hard-to-diagnose haemolysis cases?